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Elimination of Schistosoma mansoni in infected mice by slow release of artemisone

D. Gold, M. Alian, A. Domb, Y. Karawani, M. Jbarien, J. Chollet, R. K. Haynes, H. N. Wong, V. Buchholz, A. Greiner, J. Golenser

International Journal for Parasitology: Drugs and Drug Resistance 2017, 7, 241-247.

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The current treatment of schistosomiasis is based on the anti-helminthic drug praziquantel (PZQ). PZQ affects only the adult stages of schistosomes. In addition, resistance to PZQ is emerging. We suggest a drug, which could serve as a potential alternative or complement to PZQ, and as a means of treating infections at earlier, pre-granuloma stage. 

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New Review coauthored by Shaohua Jiang, Seema Agarwal and Andreas Greiner published in Angewandte Chemie

"Low-density open cellular sponges as functional materials''

DOI: 10.1002/anie.201700684

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Welcome to Macromolecular Chemistry II

Spruch der Woche

"Die reinste Form des Wahnsinns ist es, alles beim Alten zu lassen und gleichzeitig zu hoffen, dass sich etwas ändert. (The sheerest madness is to leave everything the way it is and to simultaneously hope that something will change)" Albert Einstein


"The fate of genius is to be misunderstood, but not everything is a misunderstood genius" Ralp Waldo Emmerson (1803-1882)


"Facts do not cease to exist because they are ignored” (Aldous Huxley, author of Brave New World)


"Die Ablehnung Unwichtiges zu tun, ist eine entscheidende Voraussetzung für den Erfolg“ Sir Alexander MacKenzie


"An idea that is not dangerous is unworthy of being called an idea at all“ von Oscar Wilde (Eine Idee, die nicht gewagt ist, verdient es nicht, überhaupt eine Idee genannt zu werden)

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News 18.07.2017

Electrogenic Single-Species Biocomposites as Anodes for Microbial Fuel Cells

P. Kaiser, S. Reich, D. Leykam, M. Willert-Porada, A. Greiner, R. Freitag 

Macromol. Biosci. 2017, 17, 1600442

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Integration of electrogenic microorganisms remains a challenge in biofuel cell technology. Here, synthetic biocomposites (“artificial biofilms”) are proposed. Bacteria (Shewanella oneidensis) are embedded in a hydrogel matrix (poly(vinyl alcohol)) via wet- and electrospinning, creating fibers and nonwoven gauzes. The bacteria remain viable and metabolically active. The performance is compared to S. oneidensis suspension cultures and “natural” biofilms. While lower than with the suspension cultures, the power output from the fuel cells with the artificial biofilms is higher than with the natural one. Handling, reproducibility, and stability are also better. Artificial biofilms can therefore contribute to resolving fundamental issues of design, scale up, and monosepsis in biofuel cell technology.

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